CLINICAL RELEVANCE OF MOLECULAR MARKERS IN GLIOMAS

Management of Gliomas: Relevance of Molecular Markers for Clinical Practice

Diagnostic, prognostic and predictive relevance of molecular markers in gliomas.

The advances of genome-wide 'discovery platforms' and the increasing affordability of the analysis of significant sample sizes have led to the identification of novel mutations in brain tumours that became diagnostically and prognostically relevant. The development of mutation-specific antibodies has facilitated the introduction of these convenient biomarkers into most neuropathology laboratori...

Impact of Molecular Markers on Personalised-Treatment Concepts in Gliomas

investigation of (meta)discourse markers in elt coursebooks

the present study aimed to investigate representation of discourse markers and metadiscourse markers in conversations and readings of general elt coursebook series used in the language centers of iran. to this aim, four elt coursebooks popularly taught in language centers of this country were analyzed based on fung and carter’s (2007) framework regarding discourse markers and hyland’s (2005) fr...

Molecular pathology in adult gliomas: diagnostic, prognostic, and predictive markers.

Over the past 10 years, there has been an increasing use of molecular markers in the assessment and management of adult malignant gliomas. Some molecular signatures are used diagnostically to help pathologists classify tumours, whereas others are used to estimate prognosis for patients. Most crucial, however, are those markers that are used to predict response to certain therapies, thereby dire...